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Displaying 109 of 2917 articles.
In brief: Tweaking RNA protects cells from harmful inflammation
New research has helped explain what goes wrong in Aicardi-Gouti猫res syndrome, a rare brain disorder. Patients with the disease have genetic abnormalities that may put their cells at risk of accidentally triggering an antiviral response.
In brief: Mutation explains why some people are more vulnerable to viral brain infection
Scientists identified mutations in a single gene that impair immunity to viruses in a region of the brain called the brain stem.
New images reveal how the ear’s sensory hairs take shape
Our ability to hear relies on tiny bundles of hair-like sensors inside the inner ear. Scientists have identified a key component of the machinery that makes these bundles grow in an orderly fashion.
Uncovering the early origins of Huntington’s disease
The symptoms of Huntington鈥檚 typically appear in middle age, but the disease may in fact originate much earlier. New research shows that a patient鈥檚 neural abnormalities may arise already during embryonic development鈥攕uggesting that treating the disease early may be beneficial.
3D imaging of fat reveals potential targets for new obesity treatments
With new imaging methods, scientists hope to make significant progress in the fight against obesity. A new report reveals striking images of neural projections within fat tissue, and clues for the development of new drugs.
In brief: New clues about how cells restart stalled replication
Scientists studying the cell鈥檚 DNA-copying machinery have discovered a molecular mechanism that helps reactivate it should it stop prematurely. Its function may prevent genetic errors like those that cause cancer.
Glial cells, not neurons, lead the way in brain assembly
Researchers have found that the cells directing the very first steps of brain formation are not other neurons, as scientists have long assumed. They've also uncovered previously hidden molecular pathways that attract neurons into the brain.
Targeting a single protein might treat a broad range of viruses
Scientists have identified a protein that many viruses require to spread within a host鈥攁 discovery that could lead to fighting diseases as varied as parainfluenza, West Nile, and Zika with a single drug. This finding could also lead to the development of treatments for emerging viruses.
Potential new treatment for Fragile X targets one gene to affect many
Scientists found that inhibiting a regulatory protein alters the intricate signaling chemistry that is responsible for many of the disease鈥檚 symptoms. The findings provide a path to possible therapeutics for disorders associated with Fragile X.
Inflammation trains the skin to heal faster
Scientists have found that stem cells in the skin remember an injury, helping them close recurring wounds faster. The discovery could advance research and treatment of psoriasis and other inflammatory diseases.
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